The effect of aging on cochlear amplifier: A simulation approach using a physiologically-based electro-mechanical model of the cochlea
Keywords:
Acoustics, Audio frequency amplifiers, Computer simulation, Physiology, Cochlear amplifiers, Electromechanical models, Endocochlear potentials, Human cochleas, Inner ear, Mechanical elements, Middle ears, Organ of corti, Simulation approach, Sound pressure field, Transmission line models, Traveling waveAbstract
The electrical, acoustical, and mechanical elements of the cochlea are explicitly integrated into a transmission-line model to develop a physiological interpretation of the human cochlea insofar. The model enables fundamental simulation of specific cochlear lesions such as metabolic presbyacusis. A sound pressure field in the air is transmitted via the outer and middle ear to the inner ear. It causes the stapes to vibrate resulting in a traveling wave along the organ of Corti propagating from base towards apex. As the endocochlear potential (EP) decreases, the MET produces less receptor current which, eventually leading to a decline in the force/displacement generated by the somatic motor. The CFs of the curves tend to move backwards in a presbyacusis cochlea, this result is consistent with Robles and Ruggem where in a passive cochlea, the CFs are shifted backwards.Additional Files
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