The effect of aging on cochlear amplifier: A simulation approach using a physiologically-based electro-mechanical model of the cochlea

Amin Saremi, Stefan Stenfelt

Abstract


The electrical, acoustical, and mechanical elements of the cochlea are explicitly integrated into a transmission-line model to develop a physiological interpretation of the human cochlea insofar. The model enables fundamental simulation of specific cochlear lesions such as metabolic presbyacusis. A sound pressure field in the air is transmitted via the outer and middle ear to the inner ear. It causes the stapes to vibrate resulting in a traveling wave along the organ of Corti propagating from base towards apex. As the endocochlear potential (EP) decreases, the MET produces less receptor current which, eventually leading to a decline in the force/displacement generated by the somatic motor. The CFs of the curves tend to move backwards in a presbyacusis cochlea, this result is consistent with Robles and Ruggem where in a passive cochlea, the CFs are shifted backwards.

Keywords


Acoustics; Audio frequency amplifiers; Computer simulation; Physiology; Cochlear amplifiers; Electromechanical models; Endocochlear potentials; Human cochleas; Inner ear; Mechanical elements; Middle ears; Organ of corti; Simulation approach; Sound pressure field; Transmission line models; Traveling wave

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