Recovery of vascular function after exposure to a single bout of vibration

Authors

  • Kristine Krajnak Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States
  • Stacy Waugh Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States
  • Claud Johnson Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States
  • Roger Miller Engineering and Controls Technology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States
  • Shengqiao Li Biostatistics and Epidemiology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States
  • Michael Andrew Biostatistics and Epidemiology Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26506, United States

Keywords:

Control level, Repeated measures, Residual effects, Single exposure, Vascular functions, Vibration exposure

Abstract

A model of vibration-induced dysfunction is used to determine the presence of residual effects of a single exposure to vibration on peripheral vascular function and residual effects, the number of days of rest needed for vascular function to recover after a single exposure. Rats were acclimated to the laboratory for 1 week prior to the beginning of the experiment. All data were expressed as a percent change from baseline and were analyzed using 2-way repeated measures ANOVAs. One day following exposure to vibration, vasoconstriction in response to UK-14304 is enhanced in vibrated arteries as compared to controls. The results also show that vascular responsiveness returns to control levels after a 7-day recovery period. Work rotation schedules that allow more than two days of recovery between subsequent bouts of vibration exposure may help reduce the risk of developing the vascular dysfunction that is characteristic of HAVS.

Published

2011-06-01

How to Cite

1.
Krajnak K, Waugh S, Johnson C, Miller R, Li S, Andrew M. Recovery of vascular function after exposure to a single bout of vibration. Canadian Acoustics [Internet]. 2011Jun.1 [cited 2021May17];39(2):10-1. Available from: https://jcaa.caa-aca.ca/index.php/jcaa/article/view/2332

Issue

Section

Proceedings of the Acoustics Week in Canada