Measuring conditions of cold provocation tests: A review of the literature
Keywords:Finger skin, High specificity, Sensitivity and specificity, Systolic blood pressure
AbstractMeasuring conditions of cold provocation tests (CPT) were reviewed and a new database was established. Relevant articles were identified using the PubMed database from 2002 to October 2010. A total of 35 studies were selected for this review and the published articles were from temperate and subarctics zones. Outcomes chiefly measured were the change of finger skin temperature and finger systolic blood pressure. In the 10°C, 10-mm method, both sensitivity and specificity were high while the 15°C, 5-mm method, the sensitivity was lower and the specificity was high. The 10°C, 5-mm method showed lower sensitivity and comparably high specificity. The sensitivity of the 15°C, 5-mm method is relatively low, and insufficient to provoke peripheral vascular dysfunction.
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