Monitoring fluidized-bed drying of pharmaceutical granules using acoustic sensors

Derek Daniher, Lauren Briens


Fluidized bed drying of pharmaceutical granules using acoustic monitors is described. Acoustic monitoring is non-intrusive, cheap and requires no modification to existing fluidized bed drying equipment if a microphone is externally located. It is useful monitoring tool in high-shear wet granulation, pneumatic transport and rotary drying. The application of fluidized-bed drying monitoring is based on the fact that the sound produced by the collisions of dry granules is different from sound produced by the collision of moist granules.


Drying; Fluidized beds; Granular materials; Granulation; Microphones; Pneumatics; Sensors; Acoustic Sensors; High-shear wet granulation; Moist granules; Pneumatic transport

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