In-vivo ultrasound assisted tissue engineered articular condyle

Authors

  • Tarek El-Bialy Dept. of Dentistry and Biomedical Engineering, University of Alberta, T6G 2N8, Canada
  • Hasan Uludag Dept. of Chemical and Material Engineering, University of Alberta, T6G 2N8, Canada
  • Walied Moosa Department of Mechanical Engineering, University of Alberta, T6G 2N8, Canada
  • Saranjeev Lalh Renew Oral and maxillofacial Surgery, Edmonton, T6G 2N8, Canada
  • Nadr Jomha Surgery Department, Orthopedic Surgery, University of Alberta, T6G 2N8, Canada
  • Stephen Badylak McGowan Institute for Regenerative Medicine, Pittsburgh, 15219, United States

Keywords:

Bone, Electric discharge machining, Biodegradable, Bone marrow stem cells, Cellular matrixes, Collagen sponges, Functional integrations, General anesthesias, In-vivo, Mandibular condyles, Osteogenic cells, Temporomandibular joints, Urinary bladders

Abstract

The effects of (LIPUS) on in-vivo functional integration of autologus tissue engineered mandibular condyle (TEMC) for replacement of exercised temporomandibular articular condyles was evaluated. The bone marrow stem cells (BMSC) of rabbits, isolated from their femur bones, were differentiated into chondrogenic or osteogenic cells. The cells were seeded into collagen sponges housed into biodegradable extra-cellular matrix (ECM) scaffold to from TEMCs. The urinary bladder matrix extra-cellular matrix (UBM ECM) was then lyophilized and its six sheets were laminated by vacuum pressing. The left temporomandibular joint (TMJ) in each rabbit was exercised under general anesthesia and Xylazine at a rate of 1 mL/kg. The results show a comparable morphological and dimensional features of the TEMC and normal condyle.

Published

2008-09-01

How to Cite

1.
El-Bialy T, Uludag H, Moosa W, Lalh S, Jomha N, Badylak S. In-vivo ultrasound assisted tissue engineered articular condyle. Canadian Acoustics [Internet]. 2008Sep.1 [cited 2020Sep.26];36(3):42-3. Available from: https://jcaa.caa-aca.ca/index.php/jcaa/article/view/2028

Issue

Section

Proceedings of the Acoustics Week in Canada